Neutral red uptake assay (NRU)

{
  "id": "MLC-T-AGR-004414",
  "term": "Neutral red uptake assay (NRU)",
  "field": "Agriculture and food",
  "definition": "An in-vitro cell-based approach that assesses the cellular uptake of a dye in the presence of a particular substance and is used to assess basal cytotoxicity. It has been validated in the U.S. and Europe as an alternative method in toxicology.",
  "subject": "Animals, Livestock, One Health",
  "see_also": [
    "toxicity testing"
  ],
  "references": [
    "Based upon Neutral red uptake for starting doses for acute oral toxicity [NRU Cytotoxicity (2003). TM2003-01 (US). ICCVAM/NICEATM (US). TSAR - Tracking System for Alternative methods towards Regulatory acceptance. European Commission website. Accessed 9/21/2022.",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "ensayo de captación de rojo neutro (NRU)"
  },
  "url": "https://mlchart.com/terminology/agriculture/neutral-red-uptake-assay-nru/"
}