3D searching

{
  "id": "MLC-T-CHM-000017",
  "term": "3D searching",
  "field": "Chemistry",
  "definition": "A computational method for searching a database of chemical structures to find molecules that match a query defined by three-dimensional geometric constraints. The search query can be a specific conformation of a molecule or a pharmacophore model specifying the spatial arrangement of chemical features. This technique is distinct from 2D substructure searching, which only considers the connectivity of atoms.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "3D structure",
    "pharmacophore",
    "virtual screening"
  ],
  "references": [
    "PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 240 (https://doi.org/10.1515/pac-2012-1204)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/3d-searching/"
}