Generalized transition-state theory

{
  "id": "MLC-T-CHM-004822",
  "term": "Generalized transition-state theory",
  "field": "Chemistry",
  "definition": "An extension of conventional transition-state theory that allows the dividing surface between reactants and products to be placed at any point along the reaction coordinate, not just at the saddle point. This approach aims to find the dividing surface that minimizes the flux of reactive trajectories, thereby providing a more accurate rate constant. It is particularly relevant for reactions with complex potential energy surfaces.",
  "subject": "Physical and Biophysical Chemistry",
  "see_also": [
    "canonical variational transition-state theory",
    "improved canonical variational transition-state theory",
    "microcanonical variational transition-state theory",
    "col",
    "transition state",
    "transition state theory"
  ],
  "references": [
    "PAC, 1996, 68, 149. 'A glossary of terms used in chemical kinetics, including reaction dynamics (IUPAC Recommendations 1996)' on page 166 (https://doi.org/10.1351/pac199668010149)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/generalized-transition-state-theory/"
}