Critical Effect

{
  "id": "MLC-T-ENV-006915",
  "term": "Critical Effect",
  "field": "Environment",
  "definition": "1. The first adverse effect, or its known precursor, that occurs to the most sensitive species as the dose rate of an agent increases.\n\n2. The first adverse effect, or its known precursor, that occurs as a dose rate increases. Designation is based on evaluation of overall database.\n\n3. The first adverse effect, or its known precursor, that occurs as the dose rate increases.\n\n4. The first adverse effect, or its known precursor, that occurs as the dose rate increases. [EPA Advances in Inhalation Dosimetry of Gases and Vapors with Portal of Entry Effects in the Upper Respiratory Tract EPA /600/R-09/072[\n\n5. The first adverse effect, or its known precursor, that occurs to the most sensitive species as the dose rate of an agent increases. [EPA 2003, EPA 2005b]",
  "subject": "Science and research",
  "references": [
    "Integrated Risk Information System (IRIS) Glossary; EPA 2003, EPA 2005b",
    "Terms of Environment",
    "Benchmark Dose Software (BMDS) Glossary of Terms",
    "EPA EV-Outcomes-Health Impacts",
    "Thesaurus of Terms Used in Microbial Risk Assessment"
  ],
  "url": "https://mlchart.com/terminology/environment/critical-effect/"
}