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EpiOcular™ model

Term · Environment · MLC-T-ENV-009940

A non-animal test method developed in the search for a replacement for the Draize rabbit eye test. This test is an in vitro model of the human corneal epithelium composed of normal human-derived epidermal keratinocytes and is used to evaluate the eye irritation potential of chemicals, particularly surfactants. The EpiOcular™ Model would be used in combination with other non-animal alternative tests (see Bovine Corneal Opacity and Permeability Assay).

Table 1. Record
IdentifierMLC-T-ENV-009940
FieldEnvironment
SubjectChemicals, toxics and pesticides
ReferencesToxicity Testing and Risk Assessment Glossary
Record as JSON
{
  "id": "MLC-T-ENV-009940",
  "term": "EpiOcular™ model",
  "field": "Environment",
  "term_source": "EpiOcular™ Model",
  "definition": "A non-animal test method developed in the search for a replacement for the Draize rabbit eye test. This test is an in vitro model of the human corneal epithelium composed of normal human-derived epidermal keratinocytes and is used to evaluate the eye irritation potential of chemicals, particularly surfactants. The EpiOcular™ Model would be used in combination with other non-animal alternative tests (see Bovine Corneal Opacity and Permeability Assay).",
  "subject": "Chemicals, toxics and pesticides",
  "references": [
    "Toxicity Testing and Risk Assessment Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/epioculartm-model/"
}

Record 9,691 of 29,894 in Environment terminology (MLC-0121). Request the full dataset.