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Draize Rabbit Eye Test

Term · Environment · MLC-T-ENV-008515

An acute toxicity test originally designed in 1944 by Food and Drug Administration (FDA) toxicologist John H. Draize. This test is used to determine the degree to which a chemical such as a pesticide, drug, or cosmetic, damages or irritates the eye. In this test a small amount of the substance is applied directly in the eye of a rabbit, and the rabbit is monitored for signs of redness, swelling, discharge, ulceration, hemorrhaging, cloudiness, or blindness in the tested eye. EPA currently requires all pesticides to be tested in the Draize test for eye irritation and uses the results to classify the products into one of four toxicity categories on the basis of that information.

Table 1. Record
IdentifierMLC-T-ENV-008515
FieldEnvironment
SubjectChemicals, toxics and pesticides
ReferencesToxicity Testing and Risk Assessment Glossary
Record as JSON
{
  "id": "MLC-T-ENV-008515",
  "term": "Draize Rabbit Eye Test",
  "field": "Environment",
  "definition": "An acute toxicity test originally designed in 1944 by Food and Drug Administration (FDA) toxicologist John H. Draize. This test is used to determine the degree to which a chemical such as a pesticide, drug, or cosmetic, damages or irritates the eye. In this test a small amount of the substance is applied directly in the eye of a rabbit, and the rabbit is monitored for signs of redness, swelling, discharge, ulceration, hemorrhaging, cloudiness, or blindness in the tested eye. EPA currently requires all pesticides to be tested in the Draize test for eye irritation and uses the results to classify the products into one of four toxicity categories on the basis of that information.",
  "subject": "Chemicals, toxics and pesticides",
  "references": [
    "Toxicity Testing and Risk Assessment Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/draize-rabbit-eye-test/"
}

Record 8,515 of 30,736 in Environment terminology (MLC-0121). Request the full dataset.