MLchartDataset catalogue

Isotope Dilution

Term · Environment · MLC-T-ENV-015036

A technique for mass spectrometric quantitation of an analyte of interest in which a stable isotope-labeled compound is used as both a surrogate and an internal standard for a non-labeled compound. The stable isotope-labeled compound is added to the sample that then undergoes preparation and analysis. Losses of the analyte during preparation and interferences during analysis should be mirrored in the isotope-labeled compound, and thus should not have an adverse effect on quantitation. {ORD} {OPP} {OAR/OAQPS} {OECA} {ORCR}

Table 1. Record
IdentifierMLC-T-ENV-015036
FieldEnvironment
SubjectPolicy and guidance
ReferencesForum on Environmental Measurements (FEM) Glossary
Record as JSON 
{
  "id": "MLC-T-ENV-015036",
  "term": "Isotope Dilution",
  "field": "Environment",
  "definition": "A technique for mass spectrometric quantitation of an analyte of interest in which a stable isotope-labeled compound is used as both a surrogate and an internal standard for a non-labeled compound. The stable isotope-labeled compound is added to the sample that then undergoes preparation and analysis. Losses of the analyte during preparation and interferences during analysis should be mirrored in the isotope-labeled compound, and thus should not have an adverse effect on quantitation. {ORD} {OPP} {OAR/OAQPS} {OECA} {ORCR}",
  "subject": "Policy and guidance",
  "references": [
    "Forum on Environmental Measurements (FEM) Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/isotope-dilution/"
}

Record 15,036 of 30,736 in Environment terminology (MLC-0121). Request the full dataset.