Matrix Effect

{
  "id": "MLC-T-ENV-016684",
  "term": "Matrix Effect",
  "field": "Environment",
  "definition": "Manifestation of non-target analytes or physical/ chemical characteristics of a sample that prevents the quantification of the target analyte (i.e., the compound or element of interest being effectively quantified by the test method) as it is routinely performed, typically adversely impacting the reliability of the determination. For example, a matrix effect can give rise to a high or low bias. (ORD)",
  "references": [
    "Forum on Environmental Measurements (FEM) Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/matrix-effect/"
}