Matrix effect

{
  "id": "MLC-T-CHM-007028",
  "term": "Matrix effect",
  "field": "Chemistry",
  "definition": "The influence of components other than the analyte in a sample on the analytical signal of the analyte. This effect can lead to either an increase (enhancement) or a decrease (suppression) in the measured signal, causing inaccuracies in quantitative analysis. Proper calibration strategies, such as matrix-matched calibration or standard addition, are often employed to compensate for these effects.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "matrix"
  ],
  "references": [
    "PAC, 1989, 61, 1657. 'Nomenclature for automated and mechanised analysis (Recommendations 1989)' on page 1660 (https://doi.org/10.1351/pac198961091657)",
    "PAC, 1979, 51, 2243. 'General aspects of trace analytical methods - IV. Recommendations for nomenclature, standard procedures and reporting of experimental data for surface analysis techniques' on page 2247 (https://doi.org/10.1351/pac197951112243)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/matrix-effect/"
}