Additive matrix effect

{
  "id": "MLC-T-CHM-000233",
  "term": "Additive matrix effect",
  "field": "Chemistry",
  "definition": "A matrix effect whose size does not depend on how much analyte is present, so it shifts the signal by a constant amount and alters the intercept of a linear calibration line while leaving its slope unchanged. Alternative names are translational effect and background interference. Subtracting a matrix-matched blank corrects it, whereas standard addition does not, because that method only compensates for effects that change the slope.",
  "synonyms": [
    "background interference",
    "translational matrix effect"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "blank correction"
  ],
  "references": [
    "PAC, 2021, 93, 997. 'Metrological and quality concepts in analytical chemistry (IUPAC Recommendations 2021)' on page 999 (https://doi.org/10.1515/pac-2019-0819)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/additive-matrix-effect/"
}