Multistage Model

{
  "id": "MLC-T-ENV-017949",
  "term": "Multistage Model",
  "field": "Environment",
  "definition": "1. A mathematical function used to extrapolate the probability of cancer from animal bioassay data.\n\n2. A mathematical function used to extrapolate the probability of cancer from animal bioassay data, using the form: [See PDF page 144 for formula http://water.epa.gov/scitech/swguidance/standards/upload/2007_10_01_criteria_humanhealth_microbial_thesaurus_microbial-thesaurus.pdf] P(d) = 1 - e where: P(d) = probability of cancer from a continuous, lifetime exposure rate d; qi = fitted dose coefficients of model; i = 0, 1, . . ., k; and k = number of stages selected through best fit of the model, no greater than one less than the number of available dose groups.\n\n3. Mathematical function used to extrapolate the probability of cancer from animal bioassay data.",
  "subject": "Health and safety",
  "references": [
    "Integrated Risk Information System (IRIS) Glossary",
    "EPA 2003, EPA 2004"
  ],
  "url": "https://mlchart.com/terminology/environment/multistage-model/"
}