Toxicogenomics

{
  "id": "MLC-T-ENV-028417",
  "term": "Toxicogenomics",
  "field": "Environment",
  "definition": "1. Study of the roles that genes play in the biological responses to environmental toxicants and stressors by the collection, interpretation, and storage of information about gene and protein activity.\n\n2. The study of how genomes respond to environmental stressors or toxicants. Combines genome-wide mRNA expression profiling with protein expression patterns using bioinformatics to understand the role of gene-environment interactions in disease and dysfunction.",
  "subject": "Chemicals, toxics and pesticides",
  "references": [
    "Toxicity Testing and Risk Assessment Glossary",
    "Glossary: Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA: EPA Science Policy Council at http://www.epa.gov/osa/pdfs/EPA-Genomics-White-Paper.pdf. Quotation from U.S. Department of Energy, Oak Ridge National Laboratory, Human Genome Project Information, Genome Glossary. http://www.ornl.gov/sci/techresources/Human_Genome/glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/toxicogenomics/"
}