anti-Caprin-1 monoclonal antibody TRK-950

{
  "id": "MLC-T-ONC-010198",
  "term": "anti-Caprin-1 monoclonal antibody TRK-950",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody directed against cell cycle associated protein 1 (cytoplasmic activation- and proliferation-associated protein 1; Caprin-1; CAPRIN1; RNA granule protein 105; RNG105), with potential antineoplastic activity. Upon administration, anti-Caprin-1 monoclonal antibody TRK-950 targets and binds to Caprin-1 expressed on tumor cells. This may induce antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP), thereby killing Caprin-1-expressing tumor cells. Caprin-1 is overexpressed on certain tumor cell types and plays a key role in tumor cell proliferation and metastasis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-caprin-1-monoclonal-antibody-trk-950/"
}