anti-CD38 monoclonal antibody TJ202/MOR202

{
  "id": "MLC-T-ONC-010359",
  "term": "anti-CD38 monoclonal antibody TJ202/MOR202",
  "field": "Oncology and biomedicine",
  "definition": "A fully human monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential antineoplastic activity. Anti-CD38 monoclonal antibody TJ202/MOR202 specifically binds to CD38 on CD38-positive tumor cells. This may trigger antitumoral antibody-dependent cellular cytotoxicity (ADCC) and may eventually lead to cell lysis in CD38-expressing tumor cells. CD38, a type II transmembrane glycoprotein, is present on various immune cells and hematologic malignancies, and its expression has been correlated with poor prognosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-cd38-monoclonal-antibody-tj202-mor202/"
}