anti-Ep-CAM monoclonal antibody ING-1

{
  "id": "MLC-T-ONC-010633",
  "term": "anti-Ep-CAM monoclonal antibody ING-1",
  "field": "Oncology and biomedicine",
  "definition": "An engineered monoclonal antibody (MAb) directed against the tumor-associated antigen (TAA) human epithelial cell adhesion molecule (Ep-CAM; EpCAM; CD326), with potential antitumor activity. Upon administration, anti-Ep-CAM monoclonal antibody ING-1 binds to Ep-CAM, which may result in a cytotoxic T-lymphocyte (CTL)-mediated immune response against Ep-CAM-expressing tumor cells. Ep-CAM, a cell surface protein upregulated on many tumor cell types, promotes the proliferation, migration and invasiveness of tumor cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-ep-cam-monoclonal-antibody-ing-1/"
}