anti-EpCAM monoclonal antibody AM-928

{
  "id": "MLC-T-ONC-010632",
  "term": "anti-EpCAM monoclonal antibody AM-928",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody directed against the tumor-associated antigen (TAA) epithelial cell adhesion molecule (Ep-CAM; EpCAM; CD326), with potential antineoplastic activity. Upon administration, anti-EpCAM monoclonal antibody AM-928 targets and binds to EpCAM on EpCAM-expressing tumor cells. This inhibits EpCAM-mediated signaling and the proliferation of EpCAM-expressing tumor cells. EpCAM, a cell surface protein upregulated on many tumor cell types, promotes the proliferation, migration and invasiveness of tumor cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-epcam-monoclonal-antibody-am-928/"
}