anti-MUC16 CAR T cells 27T51

{
  "id": "MLC-T-ONC-010902",
  "term": "anti-MUC16 CAR T cells 27T51",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) human mucin-16 (MUC16, cancer antigen 125; CA125; FLJ14303), with potential immunostimulating and antineoplastic activities. Upon administration, anti-MUC16 CAR T cells 27T51 recognize and bind to MUC16-expressing tumor cells, thereby inducing selective toxicity in MUC16-expressing tumor cells. MUC16, a member of the mucin family of glycoproteins, is overexpressed on a variety of cancer cell types.",
  "synonyms": [
    "anti-MUC16 CAR-T cells 27T51",
    "anti-mucin-16 CAR T cells 27T51"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-muc16-car-t-cells-27t51/"
}