MLchartDataset catalogue

Antisense oligonucleotide GTI-2040

Term · Oncology and biomedicine · MLC-T-ONC-011085

A 20-mer antisense oligonucleotide complementary to a coding region in the mRNA of the R2 small subunit component of human ribonucleotide reductase. GTI-2040 decreases mRNA and protein levels of R2 in vitro and may inhibit tumor cell proliferation in human tumors in vivo.

Table 1. Record
IdentifierMLC-T-ONC-011085
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-011085",
  "term": "Antisense oligonucleotide GTI-2040",
  "field": "Oncology and biomedicine",
  "definition": "A 20-mer antisense oligonucleotide complementary to a coding region in the mRNA of the R2 small subunit component of human ribonucleotide reductase. GTI-2040 decreases mRNA and protein levels of R2 in vitro and may inhibit tumor cell proliferation in human tumors in vivo.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/antisense-oligonucleotide-gti-2040/"
}

Record 2,224 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.