attenuated Listeria monocytogenes ANZ-100

{
  "id": "MLC-T-ONC-011291",
  "term": "attenuated Listeria monocytogenes ANZ-100",
  "field": "Oncology and biomedicine",
  "definition": "A live-attenuated strain of the Gram-positive bacterium Listeria monocytogenes (Lm) with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, attenuated Listeria monocytogenes ANZ-100 may accumulate in and infect liver cells where it may activate a potent innate immune response and an adaptive immune response involving the by recruitment and activation of T lymphocytes. This agent may potentiate the immune response to vaccines against various liver neoplasms.",
  "synonyms": [
    "ANZ100"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/attenuated-listeria-monocytogenes-anz-100/"
}