autologous anti-CD22 CAR-T cells CLIC-2201

{
  "id": "MLC-T-ONC-011396",
  "term": "autologous anti-CD22 CAR-T cells CLIC-2201",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD22, with potential antineoplastic activity. Upon administration, autologous anti-CD22 CAR-T cells CLIC-2201 recognize and kill CD22-expressing tumor cells. CD22, a B-lineage-restricted, transmembrane phosphoglycoprotein, is expressed on malignant B cells.",
  "synonyms": [
    "CLIC-2201",
    "autologous anti-CD22 CAR T cells CLIC-2201",
    "autologous CD22-targeting CAR T cells CLIC-2201"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-anti-cd22-car-t-cells-clic-2201/"
}