autologous CAR T cells KITE-197

{
  "id": "MLC-T-ONC-011521",
  "term": "autologous CAR T cells KITE-197",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) with an as of yet undisclosed target, with potential immunomodulating and antineoplastic activities. Upon administration, autologous CAR T cells KITE-197 specifically recognize and kill tumor cells expressing the as of yet undisclosed antigen target. This results in a cytotoxic T-lymphocyte (CTL) response against these tumor cells, thereby causing tumor cell lysis.",
  "synonyms": [
    "autologous CAR-T cells KITE-197"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-car-t-cells-kite-197/"
}