MLchartDataset catalogue

dual-target CAR T cells C-4-29

Term · Oncology and biomedicine · MLC-T-ONC-013180

A preparation of human T lymphocytes that have been genetically modified to express a dual-target CAR, with potential immunostimulating and antineoplastic activities. Upon administration, the dual-target CAR T cells C-4-29 recognize and kill tumor cells expressing the two as of yet undisclosed targets. This results in a cytotoxic T-lymphocyte (CTL) response against these tumor cells, thereby causing tumor cell lysis.

Table 1. Record
IdentifierMLC-T-ONC-013180
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013180",
  "term": "dual-target CAR T cells C-4-29",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of human T lymphocytes that have been genetically modified to express a dual-target CAR, with potential immunostimulating and antineoplastic activities. Upon administration, the dual-target CAR T cells C-4-29 recognize and kill tumor cells expressing the two as of yet undisclosed targets. This results in a cytotoxic T-lymphocyte (CTL) response against these tumor cells, thereby causing tumor cell lysis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dual-target-car-t-cells-c-4-29/"
}

Record 6,275 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.