MLchartDataset catalogue

Binetrakin

Term · Oncology and biomedicine · MLC-T-ONC-012017

A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B cells and enhancing their ability to present antigens to T cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).

Table 1. Record
IdentifierMLC-T-ONC-012017
FieldOncology and biomedicine
AbbreviationIL-4
SynonymsB-cell stimulatory factor 1; interleukin 4 (human) 129; B-cell stimulating factor; recombinant human IL-4; T-cell growth factor 2; interleukin-4; B-cell growth factor; B-cell proliferating factor; mast cell growth factor-2
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-012017",
  "term": "Binetrakin",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B cells and enhancing their ability to present antigens to T cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).",
  "abbreviation": "IL-4",
  "synonyms": [
    "B-cell stimulatory factor 1",
    "interleukin 4 (human) 129",
    "B-cell stimulating factor",
    "recombinant human IL-4",
    "T-cell growth factor 2",
    "interleukin-4",
    "B-cell growth factor",
    "B-cell proliferating factor",
    "mast cell growth factor-2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/binetrakin/"
}

Record 3,554 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.