Binetrakin
Term · Oncology and biomedicine · MLC-T-ONC-012017
A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B cells and enhancing their ability to present antigens to T cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).
| Identifier | MLC-T-ONC-012017 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | IL-4 |
| Synonyms | B-cell stimulatory factor 1; interleukin 4 (human) 129; B-cell stimulating factor; recombinant human IL-4; T-cell growth factor 2; interleukin-4; B-cell growth factor; B-cell proliferating factor; mast cell growth factor-2 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012017",
"term": "Binetrakin",
"field": "Oncology and biomedicine",
"definition": "A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B cells and enhancing their ability to present antigens to T cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).",
"abbreviation": "IL-4",
"synonyms": [
"B-cell stimulatory factor 1",
"interleukin 4 (human) 129",
"B-cell stimulating factor",
"recombinant human IL-4",
"T-cell growth factor 2",
"interleukin-4",
"B-cell growth factor",
"B-cell proliferating factor",
"mast cell growth factor-2"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/binetrakin/"
}
Record 3,554 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.