CMV pp65 peptide

{
  "id": "MLC-T-ONC-012677",
  "term": "CMV pp65 peptide",
  "field": "Oncology and biomedicine",
  "definition": "A peptide derived from cytomegalovirus (CMV) internal matrix protein pp65. CMV pp65 peptide antigen is used in recombinant vaccinia virus as an HLA-A-restricted epitope to produce vaccines and specific CD8+ and CD4+ cell responses against CMV infection, a serious complication of allogeneic bone marrow transplantation (BMT). In BMT, CMV infection may be prevented by passive immunization with donor-derived CMV-pp65-specific T-cell clones if provided early post-BMT.",
  "abbreviation": "CMV-PEP",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cmv-pp65-peptide/"
}