copper Cu 64-Tz-SarAr
Term · Oncology and biomedicine · MLC-T-ONC-012765
A radioconjugate composed of a tetrazine-based molecule linked to a SarAr chelator and labeled with the radionuclide copper Cu 64, with potential use as a tracer during positron emission tomography (PET). Upon administration, copper Cu 64-Tz-SarAr binds to the trans-cyclooctene (TCO) moiety of a pre-administered TCO-bearing immunoconjugate, which is bound to an antigen of interest via an antibody moiety. The immunoconjugate localizes the radionuclide to and allows the imaging of target cells expressing the antigen of interest upon PET.
| Identifier | MLC-T-ONC-012765 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | 64Cu-Tz-SarAr |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012765",
"term": "copper Cu 64-Tz-SarAr",
"field": "Oncology and biomedicine",
"definition": "A radioconjugate composed of a tetrazine-based molecule linked to a SarAr chelator and labeled with the radionuclide copper Cu 64, with potential use as a tracer during positron emission tomography (PET). Upon administration, copper Cu 64-Tz-SarAr binds to the trans-cyclooctene (TCO) moiety of a pre-administered TCO-bearing immunoconjugate, which is bound to an antigen of interest via an antibody moiety. The immunoconjugate localizes the radionuclide to and allows the imaging of target cells expressing the antigen of interest upon PET.",
"synonyms": [
"64Cu-Tz-SarAr"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/copper-cu-64-tz-sarar/"
}
Record 5,316 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.