copper Cu 64 SAR-bisPSMA

{
  "id": "MLC-T-ONC-012750",
  "term": "copper Cu 64 SAR-bisPSMA",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of two human prostate-specific membrane antigen (PSMA) binding motifs linked to a SAR chelator and labeled with the positron emission tomography (PET) tracer copper Cu 64, with potential use as a tracer for PSMA-expressing tumors during positron emission tomography (PET)/computed tomography (CT). Upon administration of copper Cu 64 SAR-bisPSMA, the PSMA binding motifs target and bind to PSMA-expressing tumor cells. Upon binding, PSMA-expressing tumor cells can be detected during PET/CT imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells.",
  "synonyms": [
    "64Cu-SAR-bisPSMA",
    "64Cu SAR-bisPSMA",
    "copper Cu 64-SAR-bisPSMA"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/copper-cu-64-sar-bispsma/"
}