gusperimus

{
  "id": "MLC-T-ONC-014049",
  "term": "gusperimus",
  "field": "Oncology and biomedicine",
  "definition": "A derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells; this agent may suppress growth of certain T-cell leukemia cell lines.",
  "abbreviation": "DSG",
  "synonyms": [
    "deoxyspergualin",
    "Deoxyspergualin Hydrochloride",
    "Gusperimus Trihydrochloride"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gusperimus/"
}