IL-2 plasmid DNA/lipid complex

{
  "id": "MLC-T-ONC-014358",
  "term": "IL-2 plasmid DNA/lipid complex",
  "field": "Oncology and biomedicine",
  "definition": "An immunotherapeutic agent consisting of a plasmid DNA encoding human Interleukin-2 (IL-2) complexed with a cationic lipid, 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE), in a 5:1 ratio. Due to the lipophilic nature of this cation liposome complex, this gene transfer system may improve the efficiency of introducing the IL-2 gene into the cells, thereby increasing the production of IL-2 and inducing an immune response.",
  "synonyms": [
    "IL-2 plasmid DNA/DMRIE/DOPE lipid complex",
    "plasmid DNA IL-2 lipid complex",
    "interleukin-2 DNA/lipid complex"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/il-2-plasmid-dna-lipid-complex/"
}