itraconazole

{
  "id": "MLC-T-ONC-004554",
  "term": "itraconazole",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to prevent or treat fungal infections. It belongs to the family of drugs called antifungal agents.",
    "A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fungal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections."
  ],
  "synonyms": [
    "oriconazole"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/itraconazole/"
}