fluconazole

{
  "id": "MLC-T-ONC-003246",
  "term": "fluconazole",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug that treats infections caused by fungi.",
    "A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic activity. Mammalian cell demethylation is much less sensitive to fluconazole inhibition."
  ],
  "abbreviation": "FCZ",
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluconazole/"
}