Fluciclovine F18

{
  "id": "MLC-T-ONC-013641",
  "term": "Fluciclovine F18",
  "field": "Oncology and biomedicine",
  "definition": "A radiotracer containing a synthetic amino acid analogue of L-leucine radiolabeled with fluorine F 18 with potential diagnostic imaging use. Similar to most amino acids, fluciclovine F18 appears to enter cells through the energy-independent L-type amino acid transporter (LAT) system. As an amino acid analogue, this agent is preferentially accumulated by tumor cells due to their increased metabolic needs; however, unlike naturally occurring amino acids, this non-natural amino acid-analogue radiotracer is not metabolized. Accordingly, fluciclovine F18 accumulates in tumor cells and can potentially be used to image tumors using positron emission tomography (PET).",
  "abbreviation": "[18F]FACBC",
  "synonyms": [
    "fluciclovine (18F)",
    "anti-1-amino-3-[18F ]fluorocyclobutane-1-carboxylic acid",
    "(18F)fluciclovine",
    "18F-fluciclovine",
    "anti-(18f)FABC",
    "anti-1-amino-3-[18F]fluorocyclobutane-1-carboxylic acid"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluciclovine-f18/"
}