Flutemetamol F 18

{
  "id": "MLC-T-ONC-013733",
  "term": "Flutemetamol F 18",
  "field": "Oncology and biomedicine",
  "definition": "A radiopharmaceutical containing flutemetamol, a thioflavin derivative of Pittsburgh compound B (PiB) labeled with the radioisotope fluorine F18 that can be used to detect beta-amyloid deposition upon positron emission tomography (PET). After intravenous administration of flutemetamol F 18, the flutemetamol moiety selectively accumulates in and binds to cerebral fibrillar amyloid-beta in the brain. The fluorine F18 radioisotope moiety is detected using PET, which allows imaging and quantification of amyloid-beta density. Amyloid plaque deposition is linked to cognitive decline, including Alzheimer’s disease, and may be linked to chemotherapy-induced cognitive impairment (CICI).",
  "synonyms": [
    "fluorine F 18 flutemetamol",
    "[18F]flutemetamol",
    "[18F]FPIB",
    "[18F]GE-067",
    "flutemetamol F-18"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/flutemetamol-f-18/"
}