fluorine F 18 W372

{
  "id": "MLC-T-ONC-013700",
  "term": "fluorine F 18 W372",
  "field": "Oncology and biomedicine",
  "definition": "A radiotracer composed of W372 radiolabeled with the radioisotope fluorine F 18, with potential amyloid-beta (Abeta) peptide imaging activity upon positron emission topography (PET). Upon administration, the W372 moiety of fluorine F 18 W372 selectively targets and binds to amyloid-beta in the brain. Upon binding, amyloid-beta plaques can be visualized and detected during PET imaging. Amyloid-beta accumulates in the brain and is a key component in plaque formation in Alzheimer's disease.",
  "synonyms": [
    "[F-18] W372",
    "[F-18]W372",
    "[18F]-W372"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-w372/"
}