fluorine F 18-6-fluorodopamine

{
  "id": "MLC-T-ONC-013704",
  "term": "fluorine F 18-6-fluorodopamine",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate consisting of 6-fluorodopamine labeled with fluorine F18 (6-[18F]FDA), with potential diagnostic activity. Upon administration, 6-[18F]FDA is taken up by presynaptic sympathetic nerve endings via the norepinephrine transporter (NET) uptake-1. Once inside, 6-[18F]FDA is rapidly converted by dopamine-beta-hydroxylase into 6-[18F]fluoronorepinephrine (6-[18F]FNE) and stored into neuronal storage vesicles. Upon positron emission tomographic (PET) scanning of the F18, sympathetic innervated regions can be visualized, such as those in pheochromocytoma.",
  "abbreviation": "[18F]-6F-DA",
  "synonyms": [
    "fluorine F 18 6-fluorodopamine",
    "18F-fluorodopamine",
    "6-fluorodopamine F-18",
    "3,4-dihydroxy-6-fluorophenethylamine F-18",
    "18F]-6F-dopamine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-6-fluorodopamine/"
}