ketoconazole

{
  "id": "MLC-T-ONC-004628",
  "term": "ketoconazole",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug that treats infection caused by a fungus. It is also used as a treatment for prostate cancer because it can block the production of male sex hormones.",
    "A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a-dimethylase, a microsomal cytochrome P450-dependent enzyme, thereby disrupting synthesis of ergosterol, an important component of the fungal cell wall."
  ],
  "abbreviation": "KCZ",
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ketoconazole/"
}