MLchartDataset catalogue

MLL/MLLT1 fusion protein

Term · Oncology and biomedicine · MLC-T-ONC-015216

A fusion protein encoded by the MLL/MLLT1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to almost the entire protein ENL.

Table 1. Record
IdentifierMLC-T-ONC-015216
FieldOncology and biomedicine
SynonymsMyeloid/Lymphoid or Mixed-Lineage Leukemia Protein 1/Protein ENL Fusion Protein; MLL/ENL Fusion Protein; KMT2A/MLLT1 Fusion Protein; Histone-Lysine N-Methyltransferase MLL/Protein ENL Fusion Protein; Histone-Lysine N-Methyltransferase 2A/Protein ENL Fusion Protein
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015216",
  "term": "MLL/MLLT1 fusion protein",
  "field": "Oncology and biomedicine",
  "definition": "A fusion protein encoded by the MLL/MLLT1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to almost the entire protein ENL.",
  "synonyms": [
    "Myeloid/Lymphoid or Mixed-Lineage Leukemia Protein 1/Protein ENL Fusion Protein",
    "MLL/ENL Fusion Protein",
    "KMT2A/MLLT1 Fusion Protein",
    "Histone-Lysine N-Methyltransferase MLL/Protein ENL Fusion Protein",
    "Histone-Lysine N-Methyltransferase 2A/Protein ENL Fusion Protein"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mll-mllt1-fusion-protein/"
}

Record 11,141 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.