modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine

{
  "id": "MLC-T-ONC-015227",
  "term": "modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity. Upon administration, modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine may stimulate the host immune system to mount humoral and cytotoxic T lymphocyte responses against HER2-expressing tumor cells, resulting in tumor cell lysis. HER2, also known as ErbB-2, is a tyrosine kinase growth factor receptor and a member of the epidermal growth factor receptor family; it plays a significant role in the pathogenesis of some breast cancers.",
  "synonyms": [
    "MVA-BN-HER2 vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/modified-vaccinia-ankara-bavarian-nordic-her2-vaccine/"
}