recombinant vaccinia-NY-ESO-1 vaccine

{
  "id": "MLC-T-ONC-016471",
  "term": "recombinant vaccinia-NY-ESO-1 vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine consisting of a recombinant vaccinia viral vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with recombinant vaccinia- NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis.",
  "abbreviation": "rV-NY-ESO-1",
  "synonyms": [
    "vaccinia-NY-ESO-1 vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-vaccinia-ny-eso-1-vaccine/"
}