autologous NY-ESO-1-specific CD8-positive T lymphocytes

{
  "id": "MLC-T-ONC-011727",
  "term": "autologous NY-ESO-1-specific CD8-positive T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous CD8+ T lymphocytes specifically reactive to the cancer-testis antigen NY-ESO-1, with potential immunostimulating and antineoplastic activities. Autologous NY-ESO-1-specific CD8+ T lymphocytes were generated from T cells isolated from a particular cancer patient, which were made specifically reactive to the NY-ESO-1 antigen, expanded ex vivo, and reintroduced into the patient. These tumor-reactive T cells may stimulate a host immune response against tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1, an antigen found in normal testis, may be upregulated in various cancers.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-ny-eso-1-specific-cd8-positive-t-lymphocytes/"
}