NY-ESO-1 plasmid DNA cancer vaccine

{
  "id": "MLC-T-ONC-015563",
  "term": "NY-ESO-1 plasmid DNA cancer vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A plasmid DNA encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1 with potential immunostimulating and antitumor activities. Upon adninstration, NY-ESO-1 plasmid DNA cancer vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1 is a tumor associated antigen (TAA) found in normal testes and expressed on the surfaces of various tumor cells, including melanoma, breast, bladder, prostate, lung, ovarian, and hepatocellular tumor cells.",
  "synonyms": [
    "pPJV7611 vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ny-eso-1-plasmid-dna-cancer-vaccine/"
}