Monoclonal antibody L6

{
  "id": "MLC-T-ONC-015266",
  "term": "Monoclonal antibody L6",
  "field": "Oncology and biomedicine",
  "definition": "A murine IgG2a monoclonal antibody with potential antineoplastic activity. Monoclonal antibody L6 binds to the L6 antigen, a cell surface glycoprotein overexpressed in many carcinomas, and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against L6-expressing tumor cells. This agent may be conjugated with various toxins in order to target their cytotoxic activity to tumor cells expressing the L6 antigen.",
  "abbreviation": "MOAB L6",
  "synonyms": [
    "L6"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-l6/"
}