neoantigen-based therapeutic cancer vaccine GRT-R904

{
  "id": "MLC-T-ONC-015479",
  "term": "neoantigen-based therapeutic cancer vaccine GRT-R904",
  "field": "Oncology and biomedicine",
  "definition": "A cancer boosting vaccine consisting of tumor-specific shared neoantigens, which are immunogenic and unique across a subset of patients, with potential immunostimulating and antineoplastic activities. Upon administration of the neoantigen-based therapeutic cancer vaccine GRT-R904, which is administered after the initial administration of the priming vaccine GRT-C903, the peptides stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against the shared neoantigens expressed on tumor cells, which results in tumor cell lysis.",
  "synonyms": [
    "Shared Neoantigen Boosting Cancer Vaccine GRT-R904",
    "boosting cancer vaccine GRT-R904",
    "shared neoantigen cancer vaccine boost GRT-R904",
    "boosting vaccine GRT-R904"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/neoantigen-based-therapeutic-cancer-vaccine-grt-r904/"
}