MVA tumor-specific neoantigen boosting vaccine MVA-209-FSP
Term · Oncology and biomedicine · MLC-T-ONC-015378
An off-the-shelf neoantigen boosting vaccine comprised of a modified Vaccinia virus Ankara (MVA) encoding tumor-specific neoantigens (TSNAs) derived from the same as of yet undisclosed frameshift peptides (FSPs) targeted by the priming vaccine, great ape adenoviral tumor-specific neoantigen priming vaccine GAd-209-FSP, with potential immunostimulatory and antineoplastic activities. Following intramuscular administration of the priming vaccine GAd-209-FSP, the booster MVA tumor-specific neoantigen boosting vaccine MVA-209-FSP may serve to further expand and improve the phenotyping of antigen-specific T-cells targeted to the tumor cells expressing the TSNAs.
| Identifier | MLC-T-ONC-015378 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | Modified Vaccinia Ankara Tumor-specific Neoantigen Boosting Vaccine MVA-209-FSP; Modified Vaccinia Virus Ankara Tumor-specific Neoantigen Boosting Vaccine MVA-209-FSP |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015378",
"term": "MVA tumor-specific neoantigen boosting vaccine MVA-209-FSP",
"field": "Oncology and biomedicine",
"definition": "An off-the-shelf neoantigen boosting vaccine comprised of a modified Vaccinia virus Ankara (MVA) encoding tumor-specific neoantigens (TSNAs) derived from the same as of yet undisclosed frameshift peptides (FSPs) targeted by the priming vaccine, great ape adenoviral tumor-specific neoantigen priming vaccine GAd-209-FSP, with potential immunostimulatory and antineoplastic activities. Following intramuscular administration of the priming vaccine GAd-209-FSP, the booster MVA tumor-specific neoantigen boosting vaccine MVA-209-FSP may serve to further expand and improve the phenotyping of antigen-specific T-cells targeted to the tumor cells expressing the TSNAs.",
"synonyms": [
"Modified Vaccinia Ankara Tumor-specific Neoantigen Boosting Vaccine MVA-209-FSP",
"Modified Vaccinia Virus Ankara Tumor-specific Neoantigen Boosting Vaccine MVA-209-FSP"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/mva-tumor-specific-neoantigen-boosting-vaccine-mva-209-fsp/"
}
Record 11,473 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.