nisevokitug

{
  "id": "MLC-T-ONC-015515",
  "term": "nisevokitug",
  "field": "Oncology and biomedicine",
  "definition": "A monoclonal antibody directed against human transforming growth factor beta (TGF-beta), with potential antineoplastic activity. Upon administration, nisevokitug targets and binds to TGF-beta, thereby preventing the activation of TGF-beta-mediated signaling pathways. TGF-beta, a pro-inflammatory mediator that is mutated and/or overexpressed in a number of cancer cell types, is involved in cancer cell proliferation and migration, and tumor progression.",
  "synonyms": [
    "anti-TGF-beta monoclonal antibody NIS793"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/nisevokitug/"
}