anti-TGF-beta RII monoclonal antibody IMC-TR1

{
  "id": "MLC-T-ONC-011111",
  "term": "anti-TGF-beta RII monoclonal antibody IMC-TR1",
  "field": "Oncology and biomedicine",
  "definition": "A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1 specifically targets and binds to TGF-beta R11, thereby preventing the activation of TGF-beta RII-mediated signaling pathways. TGF-beta RII is mutated in a number of cancer cell types and is involved in cancer cell proliferation and tumor progression.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-tgf-beta-rii-monoclonal-antibody-imc-tr1/"
}