Oregovomab

{
  "id": "MLC-T-ONC-006142",
  "term": "Oregovomab",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A monoclonal antibody that is being studied in the treatment of ovarian cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Oregovomab binds to the CA-125 antigen, which is found on most ovarian cancer cells. Also called OvaRex.",
    "A murine monoclonal antibody that attaches to the tumor-associated antigen CA125. Vaccination with monoclonal antibody B43.13 may stimulate a host cytotoxic immune response against tumor cells that express CA125."
  ],
  "abbreviation": "MOAB B43.13",
  "synonyms": [
    "OvaRex",
    "monoclonal antibody B43.13",
    "B43.13",
    "OvaRex monoclonal antibody B43.13"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/oregovomab/"
}