Recombinant transforming growth factor-beta-2

{
  "id": "MLC-T-ONC-016462",
  "term": "Recombinant transforming growth factor-beta-2",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant polypeptide chemically identical to or similar to the endogenous cytokine transforming growth factor-beta-2 (TGF-beta-2). TGF-beta-2 modulates cell growth and immune function and may promote or inhibit tumor growth, depending on the tumor cell type. TGF-beta-2 may also suppress host immune system recognition of and/or response to tumor cells.",
  "abbreviation": "rTGF-beta-2",
  "synonyms": [
    "glioblastoma-derived T-cell suppressor factor",
    "transforming growth factor-beta 2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-transforming-growth-factor-beta-2/"
}