MLchartDataset catalogue

recombinant adenovirus-hIFN-beta

Term · Oncology and biomedicine · MLC-T-ONC-016384

A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce caspase-mediated tumor cell apoptosis.

Table 1. Record
IdentifierMLC-T-ONC-016384
FieldOncology and biomedicine
SynonymsAd-hIFN-beta
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016384",
  "term": "recombinant adenovirus-hIFN-beta",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce caspase-mediated tumor cell apoptosis.",
  "synonyms": [
    "Ad-hIFN-beta"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-adenovirus-hifn-beta/"
}

Record 14,124 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.