tropisetron

{
  "id": "MLC-T-ONC-008924",
  "term": "tropisetron",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to prevent nausea and vomiting caused by cancer treatment. It is also used to prevent nausea and vomiting after surgery. Tropisetron blocks the action of the chemical serotonin, which binds to certain nerves and may trigger nausea and vomiting. Blocking serotonin may help lessen nausea and vomiting. It is a type of serotonin receptor antagonist and a type of antiemetic. It is not available in the United States.",
    "An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tropisetron/"
}