Granisetron hydrochloride

{
  "id": "MLC-T-ONC-003659",
  "term": "Granisetron hydrochloride",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to prevent nausea and vomiting caused by chemotherapy and radiation therapy and to prevent and treat nausea and vomiting after surgery in adults. Granisetron hydrochloride blocks the action of a chemical called serotonin, which binds to certain nerves and may trigger nausea and vomiting. Blocking serotonin may help lessen nausea and vomiting. Granisetron hydrochloride is a type of antiemetic and a type of serotonin receptor antagonist.",
    "The hydrochloride salt of an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting."
  ],
  "abbreviation": "GRAN",
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/granisetron-hydrochloride/"
}